You can animate traditional frame by frame and combine these techniques with digital puppets. Harmony is not only a digital puppet animation app – it does far more than that.
Harmony Advanced and Premium have bitmap painting tools, however, and quite painterly drawing is possible. Harmony Essentials does NOT offer any bitmap painting tools – only vector tools. I personally have not tried harmony or TV paint, but like I said ToonBoom worked beautifully. It was a great program and worked very well for what we needed it to do. When I was in college (computer animation) we had to take several traditional animation classes as well, and the college I attended had ToonBoom. I am sure each program has it is special features and such, but when doing traditional hand drawn animation, all the specials are not really needed. I think it comes down to preference in most cases.